Hematological Malignancies

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A new strategy for adult T-cell leukemia treatment targeting glycogen synthase kinase-3β

Clinical activity of 9-ING-41, a small molecule selective glycogen synthase kinase-3 beta (GSK-3β) inhibitor, in refractory adult T-Cell leukemia/lymphoma

The tumor suppressor protein TRAF3 modulates GSK3 activity and susceptibility of B lymphoma cells to GSK3 inhibition

GSK-3: a multifaceted player in acute leukemias

2020-AACR-9-ING-41, a GSK-3β-selective small molecule inhibitor, in combination with ruxolitinib in JAK2617F primary myelofibrosis

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

GSK-3β inhibitor, 9-ING-41, reduces cell viability and halts proliferation of B-cell lymphoma cell lines as a single agent and in combination with novel agents

Repression of GSK3 restores NK cell cytotoxicity in AML patients

GSK3 is a regulator of RAR-mediated differentiation

Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model