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ACTUATE THERAPEUTICS RECEIVES RARE PEDIATRIC DISEASE DESIGNATION FOR 9-ING-41 FOR TREATMENT OF NEUROBLASTOMA

CHICAGO, IL and FORT WORTH, TX, October 26, 2017 – Actuate Therapeutics, Inc., a clinical stage biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has granted Rare Pediatric Disease Designation to 9-ING-41, Actuate’s lead clinical development candidate, for the treatment of neuroblastoma. The Rare Pediatric Disease Designation of 9-ING for the

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ACTUATE THERAPEUTICS’ PROGRAMS HIGHLIGHTED IN CLINICAL CANCER RESEARCH

CHICAGO, IL and FORT WORTH, TX, April 3, 2017 – Actuate Therapeutics, Inc., a Chicagobased biopharmaceutical company, today announced that an article authored by its scientific founders titled “Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer” was published on March 31, 2017 in the Molecular Pathways special feature in

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DR. FRANCIS GILES JOINS ACTUATE THERAPEUTICS AS CHIEF MEDICAL OFFICER

CHICAGO, IL and FORT WORTH, TX, March 1, 2017 – Actuate Therapeutics, Inc., a Chicago-based biopharmaceutical company, today announced the appointment of Francis J. Giles, MB, MD, FRCPI, FRCPath to the newly created position of Chief Medical Officer (CMO). Dr. Giles will be responsible for advancing Actuate’s research and development initiatives, leading the clinical programs,

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