TIMELINE

2024

 
December 17, 2024

Positive Interim Phase 2 Data of Elraglusib in pancreatic cancer

August 14, 2024

Initial Public Offering

August 1, 2024
FDA Orphan Drug Designation for Elraglusib
 
February 9, 2024
The Last Patient’s First Dose of Elraglusib in pancreatic cancer
 
January 2024
Completion of Enrollment in Phase 2 clinical study in pancreatic cancer
 

2023

 
August 14, 2023
Completion of Phase 1 Trial for Oral Formulation of Elraglusib 
 
 

2022

 
February 7, 2022

Initiation of FOLFIRINOX Trial

 

2021

 
August 4, 2021

Actuate announces FDA fast track designation for 9-ING-41 in the treatment of pancreatic cancer.

October 27, 2021

Actuate announces the primary endpoint was met in the 9-ING-41 Phase 2 study in pancreatic cancer.

 

2020

 
July 31, 2020

Actuate announces initiation of Phase 2 clinical study in pancreatic cancer.

 

2018

 
February 15, 2018

The FDA accepts Actuate’s IND application for 9-ING-41 with clearance to proceed with clinical study in patients with advanced cancers.

December 17, 2018

Actuate treats first patient in Phase 1 / 2 Clinical Study of 9-ING-41 in patients with refractory cancers.

 

2017

 
March 31, 2017

Actuate technologies are featured in the Molecular Pathways section of the journal Clinical Cancer Research.

August 18, 2017

FDA grants 9-ING-41 an additional orphan drug designation for the treatment of neuroblastoma.

 

2016

 
March 29, 2016

Food and Drug Administration grants 9-ING-41 an orphan drug designation for the treatment of glioblastoma.

 

2015

 
January 16, 2015

The company is incorporated as Apotheca Therapeutics, Inc.

October 29, 2015

Actuate forms a Scientific Advisory Board.